Rongbiao Pi Selected Research

platinum 109

4/2022	PT109, a novel multi-kinase inhibitor suppresses glioblastoma multiforme through cell reprogramming: Involvement of PTBP1/PKM1/2 pathway.
9/2020	Discovery of a novel small molecule PT109 with multi-targeted effects against Alzheimer's disease in vitro and in vivo.

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Rongbiao Pi Research Topics

Disease

23	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 08/2008
10	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 07/2015 - 05/2009
8	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 02/2009
8	Multiple Sclerosis 10/2013 - 05/2009
6	Brain Ischemia (Cerebral Ischemia) 01/2022 - 04/2011
5	Glioblastoma (Glioblastoma Multiforme) 04/2022 - 01/2015
4	Glioma (Gliomas) 04/2022 - 01/2017
4	Neoplasms (Cancer) 04/2022 - 07/2017
4	Inflammation (Inflammations) 01/2022 - 03/2010
4	Neuroinflammatory Diseases 01/2022 - 07/2017
3	Cognitive Dysfunction 01/2022 - 06/2020
3	Central Nervous System Diseases (CNS Diseases) 07/2017 - 04/2013
2	Parkinson Disease (Parkinson's Disease) 02/2017 - 08/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 08/2015 - 04/2014
2	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2015 - 04/2013
2	Disease Progression 09/2014 - 04/2013
2	Cardiomegaly (Heart Hypertrophy) 07/2011 - 07/2007
2	Fibrosis (Cirrhosis) 07/2011 - 04/2007
2	Ischemia 04/2011 - 07/2007
1	Rupture 01/2022
1	Pathologic Processes 09/2020
1	Flushing 02/2020
1	Dyslipidemias (Dyslipidemia) 02/2020
1	Atherosclerosis 02/2020
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2020
1	Bone Diseases (Bone Disease) 01/2017

Drug/Important Bio-Agent (IBA)

7	Pharmaceutical PreparationsIBA 02/2020 - 07/2009
6	Acrolein (Aqualin)IBA 01/2022 - 02/2013
6	Minocycline (Cyclops)FDA LinkGeneric 05/2015 - 05/2009
5	Tacrine (Cognex)FDA Link 01/2021 - 01/2012
4	BerberineIBA 02/2015 - 07/2009
3	Therapeutic UsesIBA 04/2022 - 06/2011
3	LipopolysaccharidesIBA 01/2022 - 07/2017
3	AldehydesIBA 01/2022 - 04/2014
3	fasudil (AT 877)IBA 01/2022 - 04/2013
3	LigandsIBA 07/2019 - 02/2015
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 08/2008
3	rho-Associated KinasesIBA 07/2017 - 01/2017
3	caffeic acidIBA 03/2017 - 10/2012
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 05/2015 - 09/2010
3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 08/2013 - 04/2011
2	Phosphotransferases (Kinase)IBA 04/2022 - 09/2020
2	platinum 109IBA 04/2022 - 09/2020
2	Neuroprotective AgentsIBA 01/2021 - 02/2009
2	Glutamic Acid (Glutamate)FDA Link 01/2021 - 01/2015
2	Glycogen Synthase (Synthase I)IBA 09/2020 - 07/2007
2	Coumaric AcidsIBA 01/2018 - 01/2017
2	Rivastigmine (Exelon)FDA LinkGeneric 12/2017 - 01/2017
2	Oxygen (Dioxygen)IBA 07/2017 - 08/2013
2	Matrix Metalloproteinases (MMPs)IBA 03/2017 - 01/2017
2	ferulic acid (sodium ferulate)IBA 01/2017 - 01/2012
2	Nerve Growth Factor (NGF)IBA 07/2012 - 09/2010
2	Amyloid (Amyloid Fibrils)IBA 01/2012 - 08/2008
2	coumarinIBA 04/2011 - 03/2010
2	osthol (osthole)IBA 04/2011 - 03/2010
2	Prednisone (Sone)FDA LinkGeneric 09/2010 - 05/2009
1	antiglomerular basement membrane antibodyIBA 04/2022
1	IronIBA 01/2022
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2022
1	Actin Depolymerizing Factors (Cofilins)IBA 01/2022
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2022
1	Y 27632IBA 01/2022
1	huperzine AIBA 01/2021
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2021
1	icaritinIBA 01/2021
1	GlucocorticoidsIBA 09/2020
1	protein kinase C gamma (PRKCG)IBA 09/2020
1	Niacin (Nicotinic Acid)FDA LinkGeneric 02/2020
1	Hypolipidemic Agents (Antihyperlipidemics)IBA 02/2020
1	AntioxidantsIBA 02/2020
1	ApolipoproteinsIBA 02/2020
1	LipidsIBA 02/2020
1	Thioctic Acid (Lipoic Acid)IBA 02/2020
1	RolipramIBA 01/2020
1	tranilastIBA 01/2020
1	rheinIBA 01/2020
1	Biological ProductsIBA 01/2020
1	Amyloidogenic ProteinsIBA 12/2019
1	artenimol (dihydroartemisinin)IBA 12/2018
1	isothiocyanic acidIBA 12/2018
1	artemisinin (artemisinine)IBA 12/2018
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 07/2017
1	Interleukin-6 (Interleukin 6)IBA 07/2017
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2017
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 07/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2017
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 04/2017
1	Temozolomide (Temodar)FDA LinkGeneric 04/2017
1	AmidesIBA 03/2017
1	Advanced Glycation End ProductsIBA 01/2017
1	xanthoneIBA 01/2017
1	Mitogen-Activated Protein KinasesIBA 01/2017
1	1,3,5,8- tetrahydroxy- 2,4- bis(3- methyl- 2- butenyl)xanthoneIBA 01/2017
1	Receptor for Advanced Glycation End ProductsIBA 01/2017
1	MelatoninIBA 01/2016
1	ParaquatIBA 08/2015
1	GlucosidesIBA 07/2015

Therapy/Procedure

12	Therapeutics 01/2022 - 05/2009
1	Investigational Therapies (Experimental Therapy) 07/2019
1	Drug Therapy (Chemotherapy) 04/2017